Marie and the rest of the Kankers are nowhere to be found in the Future, but the Trojan Hamburger Marie was building can be found at the side of what's left of the Park 'n' Flush trailer park inside a big ditch full of Fusion Matter. Eddy mentions in the mission "Trailer Trash" that the Kankers "aren't around anymore".
In the Past, she is building a Trojan Hamburger, which she hopes the Eds will mistake for a real giant hamburger and unknowingly let them inside the Cul-de-Sac. She sometimes bullies the other kids, or Lee when she's not busy, into helping her build it. She gives out numerous missions, but she does not have a Nano form.