As the player is encouraged to create their own character at the start of the game, all other characters are NPCs (Non Playable Characters). These characters aid the player by giving missions, items or hints through the game so that the player can advance further. There are 96 characters from 18 series and 1 block from Cartoon Network, as well as two movies which Cartoon Network does not own. They are all listed from blocks to shows and oldest to newest.
Toonami
|
| TOM |
Dexter's Laboratory
|  |
| Dexter | Dee Dee |
| 
|
| Mandark | Computress |
|
| Major Glory |
Johnny Bravo
|
| Johnny Bravo |
The Powerpuff Girls
| 
|
| Blossom | Buttercup |
| 
|
| Bubbles | Professor Utonium |
| 
|
| Mojo Jojo | Princess |
| 
|
| Mayor | Him |
| 
|
| Fuzzy Lumkins | Ace |
Ed, Edd n Eddy
| 
|
| Ed | Edd |
| 
|
| Eddy | May Kanker |
| 
|
| Marie Kanker | Lee Kanker |
Courage the Cowardly Dog
| 
|
| Courage | Bob O'Ganoosh |
| 
|
| Magic Tree | Mel Anzana |
|
| General Tso |
Samurai Jack
| 
|
| Samurai Jack | The Scotsman |
|
The Grim Adventures of Billy & Mandy
| 
|
| Billy | Mandy |
| 
|
| Grim | Hoss Delgado |
| 
|
| Dracula | Jeff |
|
Codename: Kids Next Door
| 
|
| Numbuh One | Numbuh Two |
| 
|
| Numbuh Three | Numbuh Four |
| 
|
| Numbuh Five | Father |
| 
|
| Toiletnator | Stickybeard |
|
| Numbuh 20,000 |
Megas XLR
|
| Coop |
Foster's Home for Imaginary Friends
| 
|
| Bloo | Mac |
| 
|
| Wilt | Eduardo |
| 
|
| Coco | Frankie |
| 
|
| Mr. Herriman | Cheese |
The Life and Times of Juniper Lee
|
| Juniper Lee |
Ben 10, Ben 10: Alien Force, and Ben 10: Ultimate Alien
| 
|
| Ben Tennyson | Gwen Tennyson |
| 
|
| Grandpa Max Tennyson | Kevin E. Levin |
| 
|
| Vilgax | Hex |
| 
|
| Tetrax | Paradox |
| 
|
| Azmuth | Alan |
| 
|
| Albedo | Alien X |
| 
|
| Echo Echo | Ship |
|
| Megawhatt |
Chowder
 | 
|
| Chowder | Shnitzel |
| 
|
| Kimchi | Wisdom Tooth |
|
| Sour Ron |
Johnny Test
| 
|
| Johnny Test | Dukey |
The Marvelous Misadventures of Flapjack
| 
|
| Flapjack | Candy Wife |
The Secret Saturdays
| 
|
| Zak Saturday | Doc Saturday |
| 
|
| Drew Saturday | Fiskerton |
| 
|
| Zon | V.V. Argost |
|
| Chupacabra |
Adventure Time with Finn and Jake
| 
| |
| Finn the Human | Jake the Dog | |
| 
| |
| Ice King | Princess Bubblegum | |
| 
| |
| Reaper | Stanley |
|
| Gunter |
Generator Rex
| 
|
| Rex | Agent Six |
|
| Bobo Haha |
Sym-Bionic Titan
| 
|
| Lance | Ilana |
|
